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1.
PLoS One ; 16(5): e0250735, 2021.
Artículo en Inglés | MEDLINE | ID: covidwho-1218422

RESUMEN

As the Coronavirus-2019 (COVID-19) pandemic continues, multiple therapies are rapidly being evaluated for efficacy in clinical trials. Clinical trials should be racially and ethnically representative of the population that will eventually benefit from these medications. There are multiple potential barriers to racial and ethnic minority enrollment in clinical trials, one of which could be that inclusion and exclusion criteria select for certain racial or ethnic groups disproportionately. In this observational cohort study at a single health care system, we examined if there were differences in eligibility for treatment with remdesivir based on clinical trial criteria for racial and ethnic minorities compared to non-Hispanic Whites. 201 electronic medical record charts were reviewed manually. Self-identified Whites were older than other racial or ethnic groups. At the time of presentation, Black, Latinx, and White participants met inclusion criteria for remdesivir at similar rates (72%, 80%, and 73% respectively), and exclusion criteria at similar rates (43%, 38% and 49% for Black, Latinx and White participants respectively). In this study, there was no difference in eligibility for remdesivir based on race or ethnicity alone.


Asunto(s)
Adenosina Monofosfato/análogos & derivados , Alanina/análogos & derivados , Antivirales/uso terapéutico , Tratamiento Farmacológico de COVID-19 , Adenosina Monofosfato/uso terapéutico , Adulto , Negro o Afroamericano , Anciano , Anciano de 80 o más Años , Alanina/uso terapéutico , Atención a la Salud , Determinación de la Elegibilidad , Femenino , Hispánicos o Latinos , Humanos , Masculino , Persona de Mediana Edad , Grupos Minoritarios , SARS-CoV-2/efectos de los fármacos , Estados Unidos/epidemiología , Población Blanca , Adulto Joven
2.
Ann Allergy Asthma Immunol ; 125(5): 600-602, 2020 11.
Artículo en Inglés | MEDLINE | ID: covidwho-693736
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